Ace View of B0334.11 | |||
B0334.11 Details | |||
Description | ooc-3 encodes a nematode-specific protein with a predicted signal sequence, four predicted transmembrane domains, and two putative PEST sequences; OOC-3 is probably localized to the endoplasmic reticulum (ER), and is maternally required for correct localization of PAR-2 and PAR-3 in the P1 blastomere of the two-cell stage embryo; specifically, OOC-3 is required for restricting PAR-3 to the anterior cortex of the P1 blastomere to assure PAR-2 localization at the posterior cortex; more generally, OOC-3 is required to establish asymmetrical anterior-posterior cortical domains and spindle orientation in P1. | ||
GO Terms | establishment and/or maintenance of cell polarity (GO:0007163) ; mitotic spindle orientation (GO:0000132) ; asymmetric protein localization (GO:0008105) ; endoplasmic reticulum (GO:0005783) ; molecular_function unknown (GO:0005554) | ||
Location | II:11492738..11495621 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Cenix:145-c8 | |||
Embryonic Phenotypes | Emb Penetrance None reported | ||
Adult Phenotypes | Complex Phenotype |
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RNAi Reagent Name & Type | Cenix:145-c8 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | early embryonic: Complex Phenotype | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
JA:B0334.11 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_B0334.11 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Gene Plot of B0334.11 | |||