Ace View of B0395.1 | |||||
B0395.1 Details | |||||
Description | nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells; NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton. | ||||
Homology Group (KOG) | Sodium/hydrogen exchanger protein |
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GO Terms | solute:hydrogen antiporter activity (GO:0015299) ; regulation of pH (GO:0006885) ; integral to membrane (GO:0016021) ; sodium:hydrogen antiporter activity (GO:0015385) ; sodium ion transport (GO:0006814) | ||||
Location | X:16018202..16022058 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Cenix:58-c4 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:58-c4 (PCR reagent) | ||||
Delivery Method | Injection | ||||
Remark | 3/3 tests are wildtype. | ||||
Laboratory | TH | ||||
Date | 2005-3-24 | ||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||
JA:B0395.1 | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_B0395.1 (PCR reagent) | ||||
Laboratory | JA | ||||
Date | 2003-1-10 | ||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||
Simmer:B0395.1:Repeat_a | |||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_B0395.1 (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Simmer:B0395.1:Repeat_b | |||||
Larval Phenotypes | Gro
could not be confirmed by re-testing |
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RNAi Reagent Name & Type | sjj_B0395.1 (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Simmer:B0395.1:Screen | |||||
Adult Phenotypes | Unc
could not be confirmed by re-testing |
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RNAi Reagent Name & Type | sjj_B0395.1 (PCR reagent) | ||||
Laboratory | NL | ||||
Date | 2003-10-01 | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Gene Plot of B0395.1 | |||||