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Gene/ORF B0395.1 (nhx-1) Ace View of B0395.1
B0395.1 Details Help
Description  nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells; NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton.
Homology Group (KOG)  Sodium/hydrogen exchanger protein
GO Terms  solute:hydrogen antiporter activity (GO:0015299) ; regulation of pH (GO:0006885) ; integral to membrane (GO:0016021) ; sodium:hydrogen antiporter activity (GO:0015385) ; sodium ion transport (GO:0006814)
Location   X:16018202..16022058
RNAi Phenotypes
Larva Gro
Adult Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:58-c4
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:58-c4 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:B0395.1
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_B0395.1 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:B0395.1:Repeat_a
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_B0395.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:B0395.1:Repeat_b
Larval Phenotypes  Gro could not be confirmed by re-testing
RNAi Reagent Name & Type sjj_B0395.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:B0395.1:Screen
Adult Phenotypes  Unc could not be confirmed by re-testing
RNAi Reagent Name & Type sjj_B0395.1 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of B0395.1 Browse using GBrowse
Gene Map