| Ace View of C03D6.3 | |||||||||
| C03D6.3 Details | |||||||||
| Description | cel-1 encodes a mRNA capping enzyme, with a N-terminal region with RNA triphosphatase activity and a C-terminal region containing motifs found in yeast and vaccinia virus capping enzyme guanylytransferases; cel-1 is required for embryonic viability, body morphology, and vulval development. | ||||||||
| Homology Group (KOG) | mRNA capping enzyme, guanylyltransferase (alpha) subunit |
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| GO Terms | mRNA capping (GO:0006370) ; intracellular (GO:0005622) ; RNA dependent ATPase activity (GO:0008186) ; protein tyrosine/serine/threonine phosphatase activity (GO:0008138) ; protein amino acid dephosphorylation (GO:0006470) ; mRNA guanylyltransferase activity (GO:0004484) ; mRNA processing (GO:0006397) ; protein phosphatase activity (GO:0004721) | ||||||||
| Location | I:9664852..9669052 | ||||||||
| RNAi Phenotypes |
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| External Links |    |
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| Associated RNAi Experiments | |||||||||
| Cenix:234-d2 | |||||||||
| Adult Phenotypes | WT |
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| RNAi Reagent Name & Type | Cenix:234-d2 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Remark | Wildtype results in all three tests. | ||||||||
| Laboratory | TH | ||||||||
| Date | 2005-3-24 | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| JA:C03D6.3 | |||||||||
| Larval Phenotypes | Mlt |
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| Adult Phenotypes | Bmd Dpy |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Laboratory | JA | ||||||||
| Date | 2000-11-16 | ||||||||
| Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | ||||||||
| Simmer:C03D6.3:Screen_A | |||||||||
| Larval Phenotypes | Lva |
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| Adult Phenotypes | Bmd Dpy |
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| Adult Phenotypes | Slu |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Laboratory | NL | ||||||||
| Date | 2003-10-01 | ||||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||||
| Simmer:C03D6.3:Screen_B | |||||||||
| Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||||||||
| Larval Phenotypes | Gro |
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| Adult Phenotypes | Dpy Rup Stp Unc |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Laboratory | NL | ||||||||
| Date | 2003-10-01 | ||||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||||
| [cgc5655]:C03D6.3 | |||||||||
| Adult Phenotypes | Unclassified
lipid metabolism abnormal |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Delivery Method | Bacterial_feeding | ||||||||
| Laboratory | GR | ||||||||
| Date | 2003-1-10 | ||||||||
| Reference | Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." | ||||||||
| [cgc5655]:daf-2:C03D6.3 | |||||||||
| Adult Phenotypes | WTRNAi causes no change in fat content |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Delivery Method | Bacterial_feeding | ||||||||
| Laboratory | GR | ||||||||
| Date | 2003-1-10 | ||||||||
| Strain | daf-2(e1370) | ||||||||
| Reference | Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." | ||||||||
| [cgc5655]:tph-1:C03D6.3 | |||||||||
| Adult Phenotypes | WTRNAi causes no change in fat content |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Delivery Method | Bacterial_feeding | ||||||||
| Laboratory | GR | ||||||||
| Date | 2003-1-10 | ||||||||
| Strain | tph-1(mg280) | ||||||||
| Reference | Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." | ||||||||
| [cgc5655]:tub-1:C03D6.3 | |||||||||
| Adult Phenotypes | WTRNAi causes no change in fat content |
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| RNAi Reagent Name & Type | sjj_C03D6.3 (PCR reagent) | ||||||||
| Delivery Method | Bacterial_feeding | ||||||||
| Laboratory | GR | ||||||||
| Date | 2003-1-10 | ||||||||
| Strain | tub-1(nr2004) | ||||||||
| Reference | Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." | ||||||||
| Cenix:22-b2 | |||||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
| Adult Phenotypes | WT_postembryonic_morphology |
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| RNAi Reagent Name & Type | Cenix:22-b2 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Remark | early embryonic: No significant defects. | ||||||||
| Laboratory | TH | ||||||||
| Date | 2005-3-24 | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| Gene Plot of C03D6.3 | |||||||||
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