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Gene/ORF C05D11.12 (let-721) Ace View of C05D11.12
C05D11.12 Details Help
Description  The let-721 gene encodes an ortholog of the human gene SIMILAR TO ELECTRON-TRANSFERRING-FLAVOPROTEIN DEHYDROGENASE (ETFDH), which when mutated leads to glutaricaciduria type IIC (OMIM:231675).
Homology Group (KOG)  Electron transfer flavoprotein ubiquinone oxidoreductase
GO Terms  electron-transferring-flavoprotein dehydrogenase activity (GO:0004174) ; electron transport (GO:0006118) ; oxidoreductase activity (GO:0016491)
Location   III:6444239..6447280
RNAi Phenotypes
Larva Lvl ; Gro
Adult Bmd
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:304-g8
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:304-g8 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C05D11.12
Embryonic Phenotypes  Emb Penetrance 90 %
Larval Phenotypes  Gro
Lvl
Adult Phenotypes  Bmd
RNAi Reagent Name & Type sjj_C05D11.12 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:C05D11.12
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_C05D11.12 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:304G8
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:304G8 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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