ORF Card Page


Gene/ORF C06A8.4 (skr-17)	Ace View of C06A8.4
C06A8.4 Details
Description	skr-17 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-17 has no known function in vivo, since skr-17(RNAi) animals are at least superficially normal, and SKR-17 does not appear to interact in vitro with any of the C. elegans cullin homologs.
Homology Group (KOG)	SCF ubiquitin ligase, Skp1 component
Location	II:7783376..7784967
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Summary
Cenix:157-c6
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:157-c6 (PCR reagent)
Delivery Method	Injection
Remark	Wildtype results in all three tests.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C06A8.4
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_C06A8.4 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_6F1
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_C06A8.4 (PCR reagent)
Delivery Method	Injection
Remark	PCR product contains flanking T7 promoter sequences
Laboratory	KK
Date	2002-11-19
Reference	Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Gene Plot of C06A8.4	*Browse using GBrowse*