Ace View of C09D8.1 | |||
C09D8.1 Details | |||
Description | ptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions. | ||
GO Terms | gastrulation (GO:0007369) ; epidermal differentiation (GO:0008544) ; synaptogenesis (GO:0007416) ; protein amino acid dephosphorylation (GO:0006470) ; adherens junction (GO:0005912) ; transmembrane receptor protein tyrosine phosphatase activity (GO:0005001) ; protein phosphatase activity (GO:0004721) ; protein tyrosine phosphatase activity (GO:0004725) | ||
Location | II:10975052..11012554 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Cenix:201-c1 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:201-c1 (PCR reagent) | ||
Delivery Method | Injection | ||
Remark | early embryonic: Overall wildtype. Subtle defects in the range of normal variability observed. | ||
Laboratory | TH | ||
Date | 2005-3-24 | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
JA:C09D8.1 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_C09D8.1 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
JA:C09D8.2 | |||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | sjj_C09D8.2 (PCR reagent) | ||
Laboratory | JA | ||
Date | 2003-1-10 | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Gene Plot of C09D8.1 | |||