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Gene/ORF C17D12.6 (spe-9) Ace View of C17D12.6
C17D12.6 Details Help
Description  spe-9 encodes a predicted plasma membrane protein with a short intracellular domain and external EGF-like repeats most closely resembling those of the Delta, Serrate, APX-1, and LAG-2 signaling ligands; SPE-9 is required autonomously in sperm for fertilization, and by homology, likely mediates an adhesive or signaling event necessary for proper oocyte fertilization; spe-9 mRNA is detected solely in animals that are engaged in spermatogenesis; the receptor for SPE-9 is not yet known.
Homology Group (KOG)  Fibrillins and related proteins containing Ca2+-binding EGF-like domains
GO Terms  fertilization (sensu Animalia) (GO:0007338) ; plasma membrane (GO:0005886) ; receptor binding (GO:0005102)
Location   I:11582333..11586435
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:58-c1
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:58-c1 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C17D12.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C17D12.6 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
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