Ace View of C25A11.4 | |||||
C25A11.4 Details | |||||
Description | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | ||||
GO Terms | embryonic development (GO:0009790) ; intercellular junction assembly and/or maintenance (GO:0045216) ; cell-cell adherens junction (GO:0005913) ; cytoskeletal protein binding (GO:0008092) | ||||
Location | X:9097881..9113935 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Wild Type RNAi Experiments | |||||
JA:C25A11.3 | WT | ||||
JA:C25A11.4 | WT | ||||
Cenix:146-f2 | WT | ||||
Cenix:34-e11 | WT | ||||
Experiments with Non-Wild Phenotypes | |||||
Simmer:C25A11.4:Screen | Emb | ||||
Simmer:C25A11.4:Repeat_a | Emb ; Gro ; Unc | ||||
Gene Plot of C25A11.4 | |||||