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Gene/ORF C25D7.3 (sdc-3) Ace View of C25D7.3
C25D7.3 Details Help
Description  sdc-3 encodes a protein that contains two mutationally separable domains: a zinc finger motif required for dosage compensation and a myosin- like putative ATP- binding region required for her-1 regulation of sex determination; SDC-3 activates dosage compensation by directing the dosage compensation protein complex to the hermaphrodite X chromosomes, and is functionally redundant with SDC-2 with respect to dosage compensation; SDC-1, SDC-2, and SDC-3 proteins form a complex.
GO Terms  dosage compensation complex assembly (sensu Drosophila) (GO:0016457) ; sex determination (GO:0007530) ; mitotic chromosome segregation (GO:0000070) ; nucleus (GO:0005634) ; transcription regulator activity (GO:0030528) ; nucleic acid binding (GO:0003676) ; zinc ion binding (GO:0008270)
Location   V:15041545..15050779
RNAi Phenotypes
Adult Dpy ; Rup
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:55-b5
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:55-b5 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C25D7.3
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C25D7.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_5C12
Adult Phenotypes  Dpy Observed in <10% of progeny.
Rup Observed in <10% of progeny.
RNAi Reagent Name & Type sjj_C25D7.3 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Gene Plot of C25D7.3 Browse using GBrowse
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