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Gene/ORF C25D7.6 (mcm-3) Ace View of C25D7.6
C25D7.6 Details Help
Description  mcm-3 encodes a member of the MCM2/3/5 family with similarity to human DNA replication licensing factor, MCM3, and affects embryonic viability.
Homology Group (KOG)  DNA replication licensing factor, MCM3 component
GO Terms  nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; DNA binding (GO:0003677) ; ATP binding (GO:0005524) ; DNA dependent ATPase activity (GO:0008094) ; DNA replication initiation (GO:0006270) ; nucleus (GO:0005634)
Location   V:15058908..15062587
RNAi Phenotypes
Early_embryo Exaggerated asynchrony ; Sister Chromatid Separation abnormal (Cross-eyed) ; Nuclei reform next to cell division remnant ; Multiple cavities ; Multiple nuclei in 1, 2, or 4-cell embryos
Adult Pvl ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:10-c1
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Sister Chromatid Separation abnormal (Cross-eyed)
RNAi Reagent Name & Type Cenix:10-c1 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
PF:GL1_1B7
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Exaggerated asynchrony
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
RNAi Reagent Name & Type sjj_C25D7.6 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
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Gene Plot of C25D7.6 Browse using GBrowse
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