Ace View of C25D7.6 | |
C25D7.6 Details | |
Description | mcm-3 encodes a member of the MCM2/3/5 family with similarity to human DNA replication licensing factor, MCM3, and affects embryonic viability. |
Homology Group (KOG) | DNA replication licensing factor, MCM3 component |
GO Terms | nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; DNA binding (GO:0003677) ; ATP binding (GO:0005524) ; DNA dependent ATPase activity (GO:0008094) ; DNA replication initiation (GO:0006270) ; nucleus (GO:0005634) |
Location | V:15058908..15062587 |
RNAi Phenotypes | |
External Links | |
Associated RNAi Experiments | |
Cenix:10-c1 | |
Embryonic Phenotypes | Emb Penetrance None reported |
Adult Phenotypes | Sister Chromatid Separation abnormal (Cross-eyed) |
RNAi Reagent Name & Type | Cenix:10-c1 (PCR reagent) |
Delivery Method | Injection |
Remark | early embryonic: Sister Chromatid Separation (Cross-eyed) |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
PF:GL1_1B7 | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Exaggerated asynchrony Multiple cavities Multiple nuclei in 1, 2, or 4-cell embryos Nuclei reform next to cell division remnant |
RNAi Reagent Name & Type | sjj_C25D7.6 (PCR reagent) |
Delivery Method | Injection |
Remark | PCR product contains flanking T7 promoter sequences |
Laboratory | KK |
Date | 2002-11-19 |
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | Movies/Stacks/Images |
Gene Plot of C25D7.6 | |