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Gene/ORF C29A12.3 (lig-1) Ace View of C29A12.3
C29A12.3 Details Help
Description  lig-1 is orthologous to the human gene LIM HOMEOBOX PROTEIN 3 ISOFORM B (LIG1; OMIM:600577), which when mutated leads to disease.
GO Terms  DNA ligase (ATP) activity (GO:0003910) ; ATP binding (GO:0005524) ; DNA replication (GO:0006260) ; DNA repair (GO:0006281) ; DNA recombination (GO:0006310)
Location   V:10816300..10819702
RNAi Phenotypes
Early_embryo Exaggerated asynchrony ; Sister Chromatid Separation abnormal (Cross-eyed) ; Multiple cavities ; EMS fails to extend anteriorly ; Multiple nuclei in 1, 2, or 4-cell embryos ; Aberrant nuclear reassembly ; Ectopic cleavage furrows ; Excessive blebbing ; Aberrant cell-cell contacts at the four-cell stage ; Nuclei reform next to cell division remnant
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:C29A12.3 Emb
PF:GL1_1E9 Aberrant cell-cell contacts at the four-cell stage ; Aberrant nuclear reassembly ; Ectopic cleavage furrows ; Emb ; EMS fails to extend anteriorly ; Exaggerated asynchrony ; Excessive blebbing ; Multiple cavities ; Multiple nuclei in 1, 2, or 4-cell embryos ; Nuclei reform next to cell division remnant
Cenix:10-e11 Emb ; Sister Chromatid Separation abnormal (Cross-eyed)
JA:C29A12.3 Emb
Gene Plot of C29A12.3 Browse using GBrowse
Gene Map