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Gene/ORF C30C11.2 (rpn-3) Ace View of C30C11.2
C30C11.2 Details Help
Homology Group (KOG)  26S proteasome regulatory complex, subunit RPN3/PSMD3
GO Terms  binding (GO:0005488)
Location   III:8446863..8449624
RNAi Phenotypes
Early_embryo Slow cell cycle ; Excessive blebbing ; P0 spindle does not rotate ; Catastrophic one-cell arrest ; Osmotically/ pressure sensitive ; Delayed at pronuclear contact ; Passage Through Meiosis defective ; Passage Through Meiosis defective
Larva Lva ; Lvl
Adult Sck ; Reduced fecundity of injected worm ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:302-h12
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Passage Through Meiosis defective
RNAi Reagent Name & Type Cenix:302-h12 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Passage Through Meiosis
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:340-f10
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Passage Through Meiosis defective
RNAi Reagent Name & Type Cenix:340-f10 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Passage Through Meiosis
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C30C11.2
Adult Phenotypes  Sck
Ste
RNAi Reagent Name & Type sjj_C30C11.2 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
PF:GL1_6E9
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Ste
Reduced fecundity of injected worm
Adult Phenotypes  Catastrophic one-cell arrest
Delayed at pronuclear contact
Excessive blebbing
Osmotically/ pressure sensitive
P0 spindle does not rotate
Slow cell cycle
RNAi Reagent Name & Type sjj_C30C11.2 (PCR reagent)
Delivery Method  Injection
Remark  PCR product contains flanking T7 promoter sequences
Laboratory  KK
Date  2002-11-19
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Simmer:C30C11.2
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_C30C11.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:302h12
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:302h12 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (C30C11.2-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:340f10
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:340f10 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (C30C11.2-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of C30C11.2 Browse using GBrowse
Gene Map