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Gene/ORF C33F10.9 (msp-40) Ace View of C33F10.9
C33F10.9 Details Help
Description  msp-40 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
GO Terms  structural molecule activity (GO:0005198)
Location   II:4824980..4826215
RNAi Phenotypes
Adult Sck
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:203-f3
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:203-f3 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype. Transparent worms mentioned in 2/3 tests are still in the range of normal variability and not significant.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C33F10.9
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C33F10.9 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of C33F10.9 Browse using GBrowse
Gene Map