Ace View of C33H5.4 | |
C33H5.4 Details | |
Description | klp-10 encodes a kinesin-like motor protein that displays similarity to diverse types of kinesin motor domains such as those found in C. elegans OSM-3, the vertebrate CHO1/MKLP proteins, and Saccharomyces cerevisiae Kip3; KLP-10 is required for embryogensis, may play a role in meiosis, and has been implicated in chromosome segregation and cell cycle progression. |
GO Terms | microtubule motor activity (GO:0003777) ; ATP binding (GO:0005524) ; microtubule-based movement (GO:0007018) ; microtubule associated complex (GO:0005875) |
Location | IV:7796704..7800782 |
RNAi Phenotypes | |
External Links | |
Associated RNAi Experiments | |
Cenix:12-b6 | |
Embryonic Phenotypes | Emb Penetrance None reported |
Adult Phenotypes | Passage Through Meiosis defective |
RNAi Reagent Name & Type | Cenix:12-b6 (PCR reagent) |
Delivery Method | Injection |
Remark | early embryonic: Polar Body Extrusion |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Cenix:219-e3 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:219-e3 (PCR reagent) |
Delivery Method | Injection |
Remark | Wildtype results in all three tests. |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
JA:C33H5.3 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | sjj_C33H5.3 (PCR reagent) |
Laboratory | JA |
Date | 2003-1-10 |
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
JA:C33H5.4 | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Him |
RNAi Reagent Name & Type | sjj_C33H5.4 (PCR reagent) |
Laboratory | JA |
Date | 2003-1-10 |
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
PF:GL1_3F3 | |
Embryonic Phenotypes | Emb Penetrance 100 % |
Adult Phenotypes | Excessive blebbing Failure to form pronucleus Indistinct maternal pronucleus Loose mitotic furrow Multiple nuclei in 1, 2, or 4-cell embryos P0 spindle positioning defect Paternal pronucleus migrates Polar bodies abnormal |
RNAi Reagent Name & Type | sjj_C33H5.4 (PCR reagent) |
Delivery Method | Injection |
Remark | PCR product contains flanking T7 promoter sequences |
Laboratory | KK |
Date | 2002-11-19 |
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | Movies/Stacks/Images |
Simmer:C33H5.4 | |
Embryonic Phenotypes | Emb Penetrance 90 % |
RNAi Reagent Name & Type | sjj_C33H5.4 (PCR reagent) |
Laboratory | NL |
Date | 2003-10-01 |
Strain | NL4256 rrf-3(pk1426) |
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Gene Plot of C33H5.4 | |