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Gene/ORF C33H5.4 (klp-10) Ace View of C33H5.4
C33H5.4 Details Help
Description  klp-10 encodes a kinesin-like motor protein that displays similarity to diverse types of kinesin motor domains such as those found in C. elegans OSM-3, the vertebrate CHO1/MKLP proteins, and Saccharomyces cerevisiae Kip3; KLP-10 is required for embryogensis, may play a role in meiosis, and has been implicated in chromosome segregation and cell cycle progression.
GO Terms  microtubule motor activity (GO:0003777) ; ATP binding (GO:0005524) ; microtubule-based movement (GO:0007018) ; microtubule associated complex (GO:0005875)
Location   IV:7796704..7800782
RNAi Phenotypes
Early_embryo Indistinct maternal pronucleus ; Paternal pronucleus migrates ; Multiple nuclei in 1, 2, or 4-cell embryos ; Excessive blebbing ; Polar bodies abnormal ; Failure to form pronucleus ; Passage Through Meiosis defective ; P0 spindle positioning defect ; Loose mitotic furrow
Adult Him
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:C33H5.3 WT
Cenix:219-e3 WT
Experiments with Non-Wild Phenotypes
Simmer:C33H5.4 Emb
JA:C33H5.4 Emb ; Him
Cenix:12-b6 Emb ; Passage Through Meiosis defective
PF:GL1_3F3 Emb ; Excessive blebbing ; Failure to form pronucleus ; Indistinct maternal pronucleus ; Loose mitotic furrow ; Multiple nuclei in 1, 2, or 4-cell embryos ; P0 spindle positioning defect ; Paternal pronucleus migrates ; Polar bodies abnormal
Gene Plot of C33H5.4 Browse using GBrowse
Gene Map