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Gene/ORF C34F11.6 (msp-49) Ace View of C34F11.6
C34F11.6 Details Help
Description  msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
GO Terms  structural molecule activity (GO:0005198)
Location   II:5193931..5195173
RNAi Phenotypes
Adult Sck ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:203-f6
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:203-f6 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C34F11.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C34F11.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of C34F11.6 Browse using GBrowse
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