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Gene/ORF C37C3.6 (ppn-1) Ace View of C37C3.6
C37C3.6 Details Help
Description  C37C3.6 encodes three isoforms of a large, novel multidomain glycoprotein orthologous to thrombospondin from Haemonchus contortus, papilin from D. melanogaster, and lacunin from Manduca sexta; the N-terminal region of C37C3.6 proteins have a domain set also found in the C-terminal region of ADAMTS matrix-associated metalloproteinases; C37C3.6 is generally required for normal cell arrangements, being required in embryos for viability and normal hypodermal enclosure, and in L1 larvae for normal excretory canal function.
GO Terms  metalloendopeptidase activity (GO:0004222) ; extracellular matrix (GO:0031012) ; serine protease inhibitor activity (GO:0004867) ; peptidase activity (GO:0008233)
Location   V:7829482..7845359
RNAi Phenotypes
Postembryonic Bli ; Larval Arrest-Late (L3/L4)
Larva Let ; Lva ; Gro
Adult Sck ; Pvl ; Pvl ; Ste ; Ste ; Unc ; Unc ; Rup ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Cenix:36-a2 Larval Arrest-Late (L3/L4)
Simmer:C37C3.6 Lva ; Unc
JA:C37C3.6 Emb ; Gro ; Pvl ; Rup ; Stp ; Unc
Gene Plot of C37C3.6 Browse using GBrowse
Gene Map