Ace View of C37F5.1 | |||
C37F5.1 Details | |||
Description | lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development. | ||
Homology Group (KOG) | Predicted transcription factor |
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GO Terms | regulation of cell fate (GO:0042659) ; negative regulation of vulval development (sensu Nematoda) (GO:0040027) ; transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; DNA binding (GO:0003677) | ||
Location | IV:2275463..2300750 | ||
RNAi Phenotypes |
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External Links | |||
Associated RNAi Experiments | |||
Wild Type RNAi Experiments | |||
JA:C37F5.1 | WT | ||
Cenix:122-c2 | WT | ||
Experiments with Non-Wild Phenotypes | |||
Simmer:C37F5.1:Screen | Muv ; Pvl | ||
Simmer:C37F5.1:Repeat_a | Muv | ||
[cgc5655]:C37F5.1 | Unclassified | ||
Gene Plot of C37F5.1 | |||