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Gene/ORF C37H5.8 (hsp-6) Ace View of C37H5.8
C37H5.8 Details Help
Description  hsp-6 encodes a mitochondrial-specific chaperone that is a member of the DnaK/Hsp70 superfamily of molecular chaperones; hsp-6 is believed to be involved in the mitochondrial unfolded protein response, as hsp-6 expression, normally broadly detected from the L1 larval through adult stages of development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-6 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development.
Homology Group (KOG)  Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily
GO Terms  ATP binding (GO:0005524)
Location   V:4823511..4826974
RNAi Phenotypes
Larva Lva ; Lva
Adult Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Simmer:C37H5.8 Emb ; Lva
Cenix:146-g5 Emb
JA:C37H5.8 Emb ; Stp
Gene Plot of C37H5.8 Browse using GBrowse
Gene Map