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Gene/ORF C43E11.10 (cdc-6) Ace View of C43E11.10
C43E11.10 Details Help
Description  cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.
Homology Group (KOG)  Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
GO Terms  nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111)
Location   I:4267698..4270688
RNAi Phenotypes
Early_embryo Sister Chromatid Separation abnormal (Cross-eyed)
Larva Lva ; Lva ; Gro
Adult Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:C43E11.9
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_C43E11.9 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Simmer:C43E11.9:Screen_A
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_C43E11.9 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:C43E11.9:Screen_B
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_C43E11.9 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Cenix:74-a3
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Sister Chromatid Separation abnormal (Cross-eyed)
RNAi Reagent Name & Type Cenix:74-a3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C43E11.10
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C43E11.10 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Gene Plot of C43E11.10 Browse using GBrowse
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