Ace View of C44B11.3 | |
C44B11.3 Details | |
Description | mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation; MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons; mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons. |
Homology Group (KOG) | Alpha tubulin |
GO Terms | mechanosensory behavior (GO:0007638) ; microtubule-based process (GO:0007017) ; response to mechanical stimulus (GO:0009612) ; microtubule (GO:0005874) ; structural constituent of cytoskeleton (GO:0005200) ; structural molecule activity (GO:0005198) ; microtubule-based movement (GO:0007018) ; GTPase activity (GO:0003924) ; GTP binding (GO:0005525) ; protein polymerization (GO:0051258) ; protein complex (GO:0043234) |
Location | III:3131166..3140077 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Wild Type RNAi Experiments | |
Cenix:327-f7 | WT |
JA:C44B11.3 | WT |
TH:327F7 | WT |
Gene Plot of C44B11.3 | |