ORF Card Page


Gene/ORF C47D12.7 (kel-1)	Ace View of C47D12.7
C47D12.7 Details
Description	kel-1 encodes a BTB/POZ- and Kelch motif-containing protein orthologous to Drosophila Kelch, which is essential for actin organization in ovarian ring canals; in C. elegans, kel-1 is required for regulating feeding during larval development and more specifically, for pharyngeal isthmus peristalsis and efficient trapping of food in the pharynx; KEL-1 is first expressed at the 1.5-fold stage of embryogenesis in the pharyngeal lumen and the nerve ring; later adult and larval expression is confined to the pharyngeal gland cells in which KEL-1 may be required for maintenance of gland cell-specific structures.
Homology Group (KOG)	Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
GO Terms	protein binding (GO:0005515)
Location	II:11688458..11696367
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Summary
Cenix:201-f8
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:201-f8 (PCR reagent)
Delivery Method	Injection
Remark	3/3 tests are wild type.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C47D12.7
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_C47D12.7 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
[cgc5655]:C47D12.7
Adult Phenotypes	Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type	sjj_C47D12.7 (PCR reagent)
Delivery Method	Bacterial_feeding
Laboratory	GR
Date	2003-1-10
Reference	Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:daf-2:C47D12.7
Adult Phenotypes	Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type	sjj_C47D12.7 (PCR reagent)
Delivery Method	Bacterial_feeding
Laboratory	GR
Date	2003-1-10
Strain	daf-2(e1370)
Reference	Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:tph-1:C47D12.7
Adult Phenotypes	Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type	sjj_C47D12.7 (PCR reagent)
Delivery Method	Bacterial_feeding
Laboratory	GR
Date	2003-1-10
Strain	tph-1(mg280)
Reference	Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:tub-1:C47D12.7
Adult Phenotypes	WTRNAi causes no change in fat content
RNAi Reagent Name & Type	sjj_C47D12.7 (PCR reagent)
Delivery Method	Bacterial_feeding
Laboratory	GR
Date	2003-1-10
Strain	tub-1(nr2004)
Reference	Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Gene Plot of C47D12.7	*Browse using GBrowse*