Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to C47E12.1.2Link to C47E12.1.1Link to C47E12.1.3Link to C47E12.13RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF C47E12.1 (srs-2) Ace View of C47E12.1
C47E12.1 Details Help
Description  srs-2 encodes a predicted cytoplasmic seryl-tRNA synthetase (SerRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of serine to its cognate tRNA and is thus required for protein biosynthesis; in C. elegans, SRS-2 activity is required for embryonic and germline development and normal postembryonic growth rates.
Homology Group (KOG)  Seryl-tRNA synthetase
GO Terms  tRNA ligase activity (GO:0004812) ; ATP binding (GO:0005524) ; amino acid activation (GO:0006418) ; serine-tRNA ligase activity (GO:0004828) ; seryl-tRNA aminoacylation (GO:0006434)
Location   IV:10003271..10005951
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects
Larva Lva ; Lva ; Gro
Adult Unc ; Ste ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Cenix:21-d8 Emb ; Severe Pleiotropic Defects
JA:C47E12.1 Emb ; Gro ; Stp
Simmer:C47E12.1 Emb ; Lva ; Ste ; Unc
Gene Plot of C47E12.1 Browse using GBrowse
Gene Map