Ace View of C47E12.5 | |||||
C47E12.5 Details | |||||
Description | uba-1 encodes a ubiquitin-activating enzyme orthologous to Saccharomyces cerevisiae UBA1 and human UBE1; UBA-1 is essential for embryogenesis and is required for germline development; by homology, UBA-1 is predicted to function in an ATP-dependent reaction that activates ubiquitin prior to its conjugation to proteins that will subsequently be degraded by the 26S proteasome; a uba-1 transcriptional reporter fusion is expressed in the larval intestine. | ||||
GO Terms | catalytic activity (GO:0003824) ; ubiquitin activating enzyme activity (GO:0004839) ; protein modification (GO:0006464) ; ubiquitin cycle (GO:0006512) ; ubiquitin-like activating enzyme activity (GO:0008642) | ||||
Location | IV:9989028..9995406 | ||||
RNAi Phenotypes |
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External Links | |||||
Associated RNAi Experiments | |||||
Experiments with Non-Wild Phenotypes | |||||
Simmer:C47E12.5 | Emb | ||||
JA:C47E12.5 | Emb ; Sck ; Ste | ||||
Cenix:36-c2 | Emb ; Passage Through Meiosis defective | ||||
Gene Plot of C47E12.5 | |||||