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Gene/ORF C47E12.8 (dhp-2) Ace View of C47E12.8
C47E12.8 Details Help
Description  The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748).
Homology Group (KOG)  Dihydroorotase and related enzymes
GO Terms  pyrimidine base catabolism (GO:0006208) ; nucleobase catabolism (GO:0046113) ; cytoplasm (GO:0005737) ; dihydropyrimidinase activity (GO:0004157) ; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (GO:0016812) ; hydrolase activity (GO:0016787)
Location   IV:9977754..9981149
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Cenix:23-b3
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:23-b3 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Overall wildtype.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:C47E12.8
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_C47E12.8 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of C47E12.8 Browse using GBrowse
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