Ace View of C54G4.8 | |||||||
C54G4.8 Details | |||||||
Description | cyc-1 encodes a component of complex III ( cytochrome c reductase) required for normal ATP production; reduction of ATP production by cyc-1(RNAi) decreases growth rate and body size, slows behavior, and increases lifespan; cyc-1 encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial | ||||||
Homology Group (KOG) | Cytochrome c1 |
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GO Terms | electron transporter activity (GO:0005489) ; electron transport (GO:0006118) ; mitochondrial electron transport chain (GO:0005746) ; heme binding (GO:0020037) | ||||||
Location | I:8022278..8024817 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
JA:C54G4.8 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % Sle | ||||||
Larval Phenotypes | Gro |
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RNAi Reagent Name & Type | sjj_C54G4.8 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2000-11-16 | ||||||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | Movies/Stacks/Images | |||||
Simmer:C54G4.8:Screen_A | |||||||
Embryonic Phenotypes | Emb Penetrance 90 % | ||||||
Larval Phenotypes | Lva |
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RNAi Reagent Name & Type | sjj_C54G4.8 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Simmer:C54G4.8:Screen_B | |||||||
Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||||||
Larval Phenotypes | Lva |
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RNAi Reagent Name & Type | sjj_C54G4.8 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Cenix:19-d1 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:19-d1 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: No significant defects. | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Gene Plot of C54G4.8 | |||||||