| Ace View of D2045.1 | |||||||||
| D2045.1 Details | |||||||||
| Description | atx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2, which when mutated leads to spinocerebellar ataxia 2 (SCA2; OMIM:183090). | ||||||||
| Location | III:10461109..10468331 | ||||||||
| RNAi Phenotypes |
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| External Links |    |
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| Associated RNAi Experiments | |||||||||
| Cenix:322-g9 | |||||||||
| Adult Phenotypes | WT |
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| RNAi Reagent Name & Type | Cenix:322-g9 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Remark | wild type | ||||||||
| Laboratory | TH | ||||||||
| Date | 2005-3-24 | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| TH:322G9 | |||||||||
| Adult Phenotypes | WTDIC phenotype -- Embryonic development normal |
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| RNAi Reagent Name & Type | TH:322G9 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Laboratory | TH | ||||||||
| Date | 2000-11-16 | ||||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
| Cenix:320-b5 | |||||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
| Adult Phenotypes | Osmotic Integrity defective |
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| RNAi Reagent Name & Type | Cenix:320-b5 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Remark | early embryonic: Osmotic Integrity | ||||||||
| Laboratory | TH | ||||||||
| Date | 2005-3-24 | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| Cenix:340-g4 | |||||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
| Adult Phenotypes | Osmotic Integrity defective |
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| RNAi Reagent Name & Type | Cenix:340-g4 (PCR reagent) | ||||||||
| Delivery Method | Injection | ||||||||
| Remark | early embryonic: Osmotic Integrity | ||||||||
| Laboratory | TH | ||||||||
| Date | 2005-3-24 | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| JA:D2045.1 | |||||||||
| Embryonic Phenotypes | Emb Penetrance 80 % | ||||||||
| RNAi Reagent Name & Type | sjj_D2045.1 (PCR reagent) | ||||||||
| Laboratory | JA | ||||||||
| Date | 2003-1-10 | ||||||||
| Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||||
| Simmer:D2045.1 | |||||||||
| Embryonic Phenotypes | Emb Penetrance 90 % | ||||||||
| RNAi Reagent Name & Type | sjj_D2045.1 (PCR reagent) | ||||||||
| Laboratory | NL | ||||||||
| Date | 2003-10-01 | ||||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||||
| TH:320b5 | |||||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
| RNAi Reagent Name & Type | TH:320b5 (PCR reagent) | ||||||||
| Remark | Phenotype comment -- Confirmed with independent dsRNA (D2045.1-RNA2; similar phenotype). | ||||||||
| Laboratory | TH | ||||||||
| Date | 2000-11-16 | ||||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
| TH:340g4 | |||||||||
| Embryonic Phenotypes | Emb Penetrance None reported | ||||||||
| RNAi Reagent Name & Type | TH:340g4 (PCR reagent) | ||||||||
| Remark | Phenotype comment -- Confirmed with independent dsRNA (D2045.1-RNA2; similar phenotype). | ||||||||
| Laboratory | TH | ||||||||
| Date | 2000-11-16 | ||||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
| Gene Plot of D2045.1 | |||||||||
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