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Gene/ORF D2085.3 Ace View of D2085.3
D2085.3 Details Help
Description  D2085.3 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:9947) (EIF2B5; OMIM:603945), which when mutated leads to disease.
Homology Group (KOG)  Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)
GO Terms  translation initiation factor activity (GO:0003743) ; regulation of translational initiation (GO:0006446)
Location   II:8661393..8665039
RNAi Phenotypes
Larva Lva ; Gro
Adult Dpy ; Pvl ; Ste ; Sma
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:55-d6
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type Cenix:55-d6 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Subtle drop in the overall pace of events in all embryos.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:D2085.3
Embryonic Phenotypes  Emb Penetrance 80 %
Larval Phenotypes  Lva
Adult Phenotypes  Dpy
RNAi Reagent Name & Type sjj_D2085.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:D2085.3
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_D2085.3 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of D2085.3 Browse using GBrowse
Gene Map