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Gene/ORF DY3.2 (lmn-1) Ace View of DY3.2
DY3.2 Details Help
Description  The lmn-1 gene encodes a nuclear lamin; LMN-1 protein is essential for the nuclear envelope localization of emerin (EMR-1) protein during during early development.
Homology Group (KOG)  Nuclear envelope protein lamin, intermediate filament superfamily
GO Terms  embryonic development (sensu Animalia) (GO:0009792) ; chromosome decondensation (GO:0051312) ; mitotic cell cycle (GO:0000278) ; chromosome segregation (GO:0007059) ; nuclear organization and biogenesis (GO:0006997) ; nuclear pore organization and biogenesis (GO:0006999) ; germ-cell development (GO:0007281) ; protein localization (GO:0008104) ; lamin filament (GO:0005638) ; nuclear membrane (GO:0005635) ; nucleoplasm (GO:0005654) ; structural molecule activity (GO:0005198)
Location   I:8762580..8766021
RNAi Phenotypes
Early_embryo Pronuclear/Nuclear Appearance abnormal ; Pna
Larva Lvl
Adult Bmd ; Unc ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:71-a6
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Pronuclear/Nuclear Appearance abnormal
RNAi Reagent Name & Type Cenix:71-a6 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Pronuclear/Nuclear Appearance
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:DY3.2
Embryonic Phenotypes  Emb Penetrance 100 %
Larval Phenotypes  Lvl
Adult Phenotypes  Pna Differentiated, not enclosed
RNAi Reagent Name & Type sjj_DY3.2 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Simmer:DY3.2:Screen_A
Embryonic Phenotypes  Emb Penetrance 90 %
Adult Phenotypes  Bmd
Ste brood size (6 out of 10)
Unc
RNAi Reagent Name & Type sjj_DY3.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:DY3.2:Screen_B
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_DY3.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Gene Plot of DY3.2 Browse using GBrowse
Gene Map