Ace View of DY3.2 | |||||||
DY3.2 Details | |||||||
Description | The lmn-1 gene encodes a nuclear lamin; LMN-1 protein is essential for the nuclear envelope localization of emerin (EMR-1) protein during during early development. | ||||||
Homology Group (KOG) | Nuclear envelope protein lamin, intermediate filament superfamily |
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GO Terms | embryonic development (sensu Animalia) (GO:0009792) ; chromosome decondensation (GO:0051312) ; mitotic cell cycle (GO:0000278) ; chromosome segregation (GO:0007059) ; nuclear organization and biogenesis (GO:0006997) ; nuclear pore organization and biogenesis (GO:0006999) ; germ-cell development (GO:0007281) ; protein localization (GO:0008104) ; lamin filament (GO:0005638) ; nuclear membrane (GO:0005635) ; nucleoplasm (GO:0005654) ; structural molecule activity (GO:0005198) | ||||||
Location | I:8762580..8766021 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Cenix:71-a6 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | Pronuclear/Nuclear Appearance abnormal |
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RNAi Reagent Name & Type | Cenix:71-a6 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Pronuclear/Nuclear Appearance | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:DY3.2 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
Larval Phenotypes | Lvl |
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Adult Phenotypes | Pna
Differentiated, not enclosed |
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RNAi Reagent Name & Type | sjj_DY3.2 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2000-11-16 | ||||||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | Movies/Stacks/Images | |||||
Simmer:DY3.2:Screen_A | |||||||
Embryonic Phenotypes | Emb Penetrance 90 % | ||||||
Adult Phenotypes | Bmd Ste brood size (6 out of 10) Unc |
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RNAi Reagent Name & Type | sjj_DY3.2 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Simmer:DY3.2:Screen_B | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_DY3.2 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Gene Plot of DY3.2 | |||||||