Description |
E04F6.3 encodes a protein that is orthologous (with 52% identity over 93% of its length) to residues 334-609 of human 17-BETA-HYDROXYSTEROID DEHYDROGENASE IV (HSD17B4; OMIM:601860, mutated in D-bifunctional protein deficiency), a protein of 736 residues whose N- and C-terminal domains are orthologous to DHS-28; E04F6.3 contains a MaoC-like domain, found in diverse enzymes (HSD17B4, peroxisomal hydratase-dehydrogenase-epimerase, and the fatty acid synthase beta subunit); E04F6.3 has no obvious function in mass RNAi assays. |