ORF Card Page


Gene/ORF EGAP2.3 (pho-1)	Ace View of EGAP2.3
EGAP2.3 Details
Description	pho-1 encodes the major C. elegans intestinal acid phosphatase; as loss of PHO-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, PHO-1 may function redundantly with other acid phosphatases; PHO-1 intestinal expression appears to be positively regulated by CKI-1, a cyclin-dependent kinase inhibitor, and negatively regulated by POP-1, a TCF/LEF transcription factor; PHO-1 is expressed along the intestinal brush border in all gut cells except the most anterior int-1 and int-2 cells, beginning at the three-fold stage of embryogenesis.
Homology Group (KOG)	Lysosomal & prostatic acid phosphatases
GO Terms	acid phosphatase activity (GO:0003993)
Location	II:5232735..5236303
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Details
Cenix:204-c9
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:204-c9 (PCR reagent)
Delivery Method	Injection
Remark	early embryonic: No significant defects.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:EGAP2.3
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_EGAP2.3 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of EGAP2.3	*Browse using GBrowse*