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Gene/ORF F01F1.12 Ace View of F01F1.12
F01F1.12 Details Help
Description  The F01F1.12 gene encodes a homolog of the human gene ADHUB, which when mutated leads to fructosemia (OMIM:229600).
GO Terms  fructose-bisphosphate aldolase activity (GO:0004332) ; glycolysis (GO:0006096)
Location   III:5873814..5876819
RNAi Phenotypes
Larva Gro
Adult Egl ; Sck ; Unc ; Stp
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:138-c5
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type Cenix:138-c5 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Classification is tentative. Overall pace of events is significantly slower than normal. Moreover, all microtubule based dynamics are jerky and irregular cortical dynamics can be observed.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:331-h2
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:331-h2 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects. In 2/3 embryos the AB nucleus migrates slightly off center but division proceeds as normal.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F01F1.12
Embryonic Phenotypes  Emb Penetrance 80 %
Adult Phenotypes  Egl
Sck
Stp
RNAi Reagent Name & Type sjj_F01F1.12 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F01F1.12
Larval Phenotypes  Gro
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_F01F1.12 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:331H2
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:331H2 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of F01F1.12 Browse using GBrowse
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