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Gene/ORF F01F1.8 (cct-6) Ace View of F01F1.8
F01F1.8 Details Help
Description  eukaryotic cytosolic chaperonin; affects viability and fertility, and is expressed in various muscle and neuronal cells: near the pharynx, near the anal sphincter, in the ventral nerve cord and the nerve ring; occasionally the expression is visible in hypodermal cells and in some vulval cells.
GO Terms  protein binding (GO:0005515) ; ATP binding (GO:0005524) ; cellular protein metabolism (GO:0044267)
Location   III:5853097..5856043
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects ; Severe Pleiotropic Defects
Larva Let ; Lva
Adult Clr ; Sck ; Pvl ; Unc ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:304-c1
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:304-c1 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:341-b5
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:341-b5 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F01F1.8
Embryonic Phenotypes  Emb Penetrance 100 %
Adult Phenotypes  Clr
Pvl
Sck
Ste
RNAi Reagent Name & Type sjj_F01F1.8 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F01F1.8
Embryonic Phenotypes  Emb Penetrance 50 - 80 %
Larval Phenotypes  Lva
Adult Phenotypes  Ste brood size (6 out of 10)
Unc
RNAi Reagent Name & Type sjj_F01F1.8 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:304C1
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:304C1 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (F01F1.8-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:341B5
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:341B5 (PCR reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (F01F1.8-RNA2; similar phenotype).
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
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