Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to F10E9.6cLink to F10E9.6a.2Link to F10E9.6a.1Link to F10E9.6bRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF F10E9.6 (mig-10) Ace View of F10E9.6
F10E9.6 Details Help
Description  mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head.
Homology Group (KOG)  Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)
GO Terms  vulval development (sensu Nematoda) (GO:0040025) ; tail morphogenesis (GO:0035121) ; oviposition (GO:0018991) ; locomotion (GO:0040011) ; regulation of cell migration (GO:0030334) ; mesoderm cell migration (GO:0008078) ; neuronal migration (GO:0001764) ; signal transduction (GO:0007165)
Location   III:8278623..8306129
RNAi Phenotypes
Larva Gro
Adult Egl ; Egl ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:302-a12
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:302-a12 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:305-h11
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:305-h11 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:310-a1
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:310-a1 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:310-b1
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:310-b1 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:314-c10
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:314-c10 (PCR reagent)
Delivery Method  Injection
Remark  wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F09G8.1
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F09G8.1 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F10E9.6
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F10E9.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
JA:F10E9.9
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F10E9.9 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F10E9.6:Repeat_a
Adult Phenotypes  Egl
Unc
RNAi Reagent Name & Type sjj_F10E9.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F10E9.6:Screen
Adult Phenotypes  Egl
Unc
RNAi Reagent Name & Type sjj_F10E9.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F10E9.7
Embryonic Phenotypes  Emb Penetrance 20 - 40 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F10E9.7 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:302A12
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:302A12 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:305H11
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:305H11 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:310A1
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:310A1 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:310B1
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:310B1 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
TH:314C10
Adult Phenotypes  WTDIC phenotype -- Embryonic development normal
RNAi Reagent Name & Type TH:314C10 (PCR reagent)
Delivery Method  Injection
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of F10E9.6 Browse using GBrowse
Gene Map