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Gene/ORF F11A5.10 (glc-1) Ace View of F11A5.10
F11A5.10 Details Help
Description  glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin.
Homology Group (KOG)  Ligand-gated ion channel
GO Terms  GABA-A receptor activity (GO:0004890) ; extracellular ligand-gated ion channel activity (GO:0005230) ; ion transport (GO:0006811) ; integral to membrane (GO:0016021) ; postsynaptic membrane (GO:0045211) ; neurotransmitter receptor activity (GO:0030594) ; membrane (GO:0016020) ; transport (GO:0006810)
Location   V:16221794..16224903
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:183-h5 (PCR reagent)
Delivery Method  Injection
Remark  Wildtype results in all three tests.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Adult Phenotypes  WT
RNAi Reagent Name & Type sjj_F11A5.10 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of F11A5.10 Browse using GBrowse
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