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Gene/ORF F11C1.6 (nhr-25) Ace View of F11C1.6
F11C1.6 Details Help
Description  nhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods.
GO Terms  transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634) ; steroid hormone receptor activity (GO:0003707) ; DNA binding (GO:0003677) ; ligand-dependent nuclear receptor activity (GO:0004879)
Location   X:13008014..13014282
RNAi Phenotypes
Postembryonic Morphology defect ; Morphology defect
Larva Mlt ; Lvl ; Lvl ; Lvl ; Lvl ; Gro
Adult Egl ; Egl ; Egl ; Egl ; Clr ; Ste ; Ste ; Sma ; Unc ; Unc ; Sterile F1
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:F11C1.6
Adult Phenotypes  Clr
Egl
Unc
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F11C1.6
Larval Phenotypes  Gro
Lvl
Adult Phenotypes  Sma
Unc
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
[cgc5655]:F11C1.6
Adult Phenotypes  Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Delivery Method  Bacterial_feeding
Laboratory  GR
Date  2003-1-10
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:daf-2:F11C1.6
Adult Phenotypes  WTRNAi causes no change in fat content
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Delivery Method  Bacterial_feeding
Laboratory  GR
Date  2003-1-10
Strain  daf-2(e1370)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:tph-1:F11C1.6
Adult Phenotypes  Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Delivery Method  Bacterial_feeding
Laboratory  GR
Date  2003-1-10
Strain  tph-1(mg280)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
[cgc5655]:tub-1:F11C1.6
Adult Phenotypes  Unclassified lipid metabolism abnormal
RNAi Reagent Name & Type sjj_F11C1.6 (PCR reagent)
Delivery Method  Bacterial_feeding
Laboratory  GR
Date  2003-1-10
Strain  tub-1(nr2004)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Cenix:53-b7
Adult Phenotypes  Sterile F1
RNAi Reagent Name & Type Cenix:53-b7 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No reproducible phenotypes found.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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