Ace View of F11C3.2 | |
F11C3.2 Details | |
Description | unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known. |
Homology Group (KOG) | Olfactomedin and related extracellular matrix glycoproteins |
GO Terms | phosphate transport (GO:0006817) ; cytoplasm (GO:0005737) |
Location | I:14871746..14875762 |
RNAi Phenotypes | No phenotypes observed. |
External Links | |
Associated RNAi Experiments | |
Cenix:147-a1 | |
Adult Phenotypes | WT |
RNAi Reagent Name & Type | Cenix:147-a1 (PCR reagent) |
Delivery Method | Injection |
Remark | 3/3 are wild type |
Laboratory | TH |
Date | 2005-3-24 |
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Gene Plot of F11C3.2 | |