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Gene/ORF F11C3.2 (unc-122) Ace View of F11C3.2
F11C3.2 Details Help
Description  unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
Homology Group (KOG)  Olfactomedin and related extracellular matrix glycoproteins
GO Terms  phosphate transport (GO:0006817) ; cytoplasm (GO:0005737)
Location   I:14871746..14875762
RNAi Phenotypes No phenotypes observed.
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:147-a1 (PCR reagent)
Delivery Method  Injection
Remark  3/3 are wild type
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
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