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Gene/ORF F18A1.2 (lin-26) Ace View of F18A1.2
F18A1.2 Details Help
Description  lin-26 encodes a putative C2H2 zinc finger-containing protein required for proper differentiation of ectodermal and mesodermal epithelial cells; LIN-26 is expressed in many different cell types including the rectal rep cells, the somatic gonad, glial cells, and hypodermal cells; ectopic LIN-26 expression during embryogenesis induces epithelial-like cell fates suggesting that LIN-26 is sufficient for epithelial differentiation.
GO Terms  ectoderm development (GO:0007398) ; epidermal differentiation (GO:0008544) ; establishment and/or maintenance of epithelial cell polarity (GO:0045197) ; nucleus (GO:0005634) ; transcription factor activity (GO:0003700)
Location   II:7681484..7685079
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology ; WT_postembryonic_morphology
Larva Mlt ; Lvl ; Lvl
Adult Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
JA:F18A1.3
Embryonic Phenotypes  Emb Penetrance 10 %
Larval Phenotypes  Lvl
Mlt
Adult Phenotypes  Unc
RNAi Reagent Name & Type sjj_F18A1.3 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F18A1.3
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_F18A1.3 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Cenix:204-d5
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:204-d5 (PCR reagent)
Delivery Method  Injection
Remark  3/3 tests are wild type.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F18A1.2
Embryonic Phenotypes  Emb Penetrance 10 %
RNAi Reagent Name & Type sjj_F18A1.2 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F18A1.2
Embryonic Phenotypes  Emb Penetrance 100 %
RNAi Reagent Name & Type sjj_F18A1.2 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Cenix:28-c5
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:28-c5 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Clear cut results.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Cenix:220-c2
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:220-c2 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: No significant defects seen in any of the recordings.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Gene Plot of F18A1.2 Browse using GBrowse
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