Ace View of F18A1.2 | |||||||
F18A1.2 Details | |||||||
Description | lin-26 encodes a putative C2H2 zinc finger-containing protein required for proper differentiation of ectodermal and mesodermal epithelial cells; LIN-26 is expressed in many different cell types including the rectal rep cells, the somatic gonad, glial cells, and hypodermal cells; ectopic LIN-26 expression during embryogenesis induces epithelial-like cell fates suggesting that LIN-26 is sufficient for epithelial differentiation. | ||||||
GO Terms | ectoderm development (GO:0007398) ; epidermal differentiation (GO:0008544) ; establishment and/or maintenance of epithelial cell polarity (GO:0045197) ; nucleus (GO:0005634) ; transcription factor activity (GO:0003700) | ||||||
Location | II:7681484..7685079 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
JA:F18A1.3 | |||||||
Embryonic Phenotypes | Emb Penetrance 10 % | ||||||
Larval Phenotypes | Lvl Mlt |
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Adult Phenotypes | Unc |
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RNAi Reagent Name & Type | sjj_F18A1.3 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2003-1-10 | ||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
Simmer:F18A1.3 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_F18A1.3 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Cenix:204-d5 | |||||||
Adult Phenotypes | WT |
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RNAi Reagent Name & Type | Cenix:204-d5 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | 3/3 tests are wild type. | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:F18A1.2 | |||||||
Embryonic Phenotypes | Emb Penetrance 10 % | ||||||
RNAi Reagent Name & Type | sjj_F18A1.2 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2003-1-10 | ||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
Simmer:F18A1.2 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
RNAi Reagent Name & Type | sjj_F18A1.2 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Cenix:28-c5 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:28-c5 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Clear cut results. | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Cenix:220-c2 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | WT_postembryonic_morphology |
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RNAi Reagent Name & Type | Cenix:220-c2 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: No significant defects seen in any of the recordings. | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
Gene Plot of F18A1.2 | |||||||