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Gene/ORF F18C12.2 (rme-8) Ace View of F18C12.2
F18C12.2 Details Help
Description  The rme-8 gene encodes a J-domain protein that is required for both receptor-mediated and fluid-phase endocytosis in coelomocytes and other cell types, and that is also required for development and viability.
Homology Group (KOG)  Endocytosis protein RME-8, contains DnaJ domain
GO Terms  receptor mediated endocytosis (GO:0006898) ; embryonic development (sensu Animalia) (GO:0009792) ; larval development (sensu Nematoda) (GO:0002119) ; vesicle membrane (GO:0012506) ; chaperone binding (GO:0051087) ; binding (GO:0005488) ; heat shock protein binding (GO:0031072) ; unfolded protein binding (GO:0051082) ; protein folding (GO:0006457)
Location   I:8083176..8095987
RNAi Phenotypes
Early_embryo Cpa ; Integrity of Membranous Organelles defective
Larva Lva ; Lva ; Lvl ; Mlt ; Gro ; Gro
Adult Bmd ; Unc ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Simmer:F18C12.3:Screen_A WT
JA:F18C12.3 WT
Experiments with Non-Wild Phenotypes
JA:F18C12.2 Bmd ; Cpa ; Emb ; Mlt ; Unc
Simmer:F18C12.2:Screen_A Emb ; Lva ; Lvl ; Unc
Cenix:84-b10 Emb ; Integrity of Membranous Organelles defective
Simmer:F18C12.3:Screen_B Gro
Simmer:F18C12.3:Repeat_b Gro
Simmer:F18C12.2:Screen_B Emb ; Lva ; Unc
Gene Plot of F18C12.2 Browse using GBrowse
Gene Map