Ace View of F22D6.3 | |||||||
F22D6.3 Details | |||||||
Description | nrs-1 encodes an asparaginyl-tRNA synthetase that is required for embryonic viability and fertility | ||||||
Homology Group (KOG) | Asparaginyl-tRNA synthetase |
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GO Terms | asparagine-tRNA ligase activity (GO:0004816) ; ATP binding (GO:0005524) ; asparaginyl-tRNA aminoacylation (GO:0006421) ; cytoplasm (GO:0005737) ; nucleic acid binding (GO:0003676) ; tRNA ligase activity (GO:0004812) ; amino acid activation (GO:0006418) ; aspartate-tRNA ligase activity (GO:0004815) ; aspartyl-tRNA aminoacylation (GO:0006422) | ||||||
Location | I:7087637..7090463 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Cenix:74-e6 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | Severe Pleiotropic Defects |
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RNAi Reagent Name & Type | Cenix:74-e6 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Severe Pleiotropic Defects | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:F22D6.3 | |||||||
Embryonic Phenotypes | Emb Penetrance 100 % | ||||||
Larval Phenotypes | Lva |
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Adult Phenotypes | Ste
brood size range (1 out of 5) |
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RNAi Reagent Name & Type | sjj_F22D6.3 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2000-11-16 | ||||||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | ||||||
Simmer:F22D6.3:Screen_A | |||||||
Larval Phenotypes | Lva |
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Adult Phenotypes | Ste
brood size (1 out of 5) |
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RNAi Reagent Name & Type | sjj_F22D6.3 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Simmer:F22D6.3:Screen_B | |||||||
Embryonic Phenotypes | Emb Penetrance 20 - 40 % | ||||||
Larval Phenotypes | Lva |
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RNAi Reagent Name & Type | sjj_F22D6.3 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
Gene Plot of F22D6.3 | |||||||