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Gene/ORF F23F12.6 (rpt-3) Ace View of F23F12.6
F23F12.6 Details Help
Description  rpt-3 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-3 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
Homology Group (KOG)  26S proteasome regulatory complex, ATPase RPT3
GO Terms  hydrolase activity (GO:0016787) ; protein catabolism (GO:0030163) ; nucleus (GO:0005634) ; cytoplasm (GO:0005737) ; nucleotide binding (GO:0000166) ; nucleoside triphosphatase activity (GO:0017111) ; ATP binding (GO:0005524)
Location   III:6489328..6491617
RNAi Phenotypes
Early_embryo Passage Through Meiosis defective
Postembryonic aldicarb_resistant ; aldicarb_resistant
Larva Let ; Let ; Lvl
Adult Sck ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Experiments with Non-Wild Phenotypes
Cenix:302-e2 Emb ; Passage Through Meiosis defective
WBRNAi00060778 Let
WBRNAi00060777 aldicarb_resistant
TH:302e2 Emb
JA:F23F12.6 Sck ; Ste
WBRNAi00060779 Let
Simmer:F23F12.6 Emb
WBRNAi00060776 aldicarb_resistant
Gene Plot of F23F12.6 Browse using GBrowse
Gene Map