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Gene/ORF F26B1.7 (let-381) Ace View of F26B1.7
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Description  let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
Homology Group (KOG)  Transcription factor of the Forkhead/HNF3 family
GO Terms  transcription factor activity (GO:0003700) ; regulation of transcription, DNA-dependent (GO:0006355) ; nucleus (GO:0005634)
Location   I:6320027..6324393
RNAi Phenotypes
Postembryonic Larval Arrest-Late (L3/L4)
Larva Gro
Adult Dpy ; Dpy ; Pvl ; Pvl ; Unc ; Unc
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
JA:F26B1.7 WT
Experiments with Non-Wild Phenotypes
Cenix:147-c7 Larval Arrest-Late (L3/L4)
Simmer:F26B1.7:Screen_A Dpy ; Pvl ; Unc
Simmer:F26B1.7:Screen_B Dpy ; Gro ; Pvl ; Unc
Gene Plot of F26B1.7 Browse using GBrowse
Gene Map