ORF Card Page


Gene/ORF F26H9.7 (uev-3)	Ace View of F26H9.7
F26H9.7 Details
Description	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
Homology Group (KOG)	Ubiquitin-protein ligase
GO Terms	ubiquitin-like activating enzyme activity (GO:0008642) ; protein modification (GO:0006464) ; ubiquitin cycle (GO:0006512)
Location	I:9311001..9312994
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Details
Cenix:161-h2
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:161-h2 (PCR reagent)
Delivery Method	Injection
Remark	Wildtype results for all three tests.
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F26H9.7
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_F26H9.7 (PCR reagent)
Laboratory	JA
Date	2000-11-16
Reference	Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Gene Plot of F26H9.7	*Browse using GBrowse*