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Gene/ORF F32A7.6 (aex-5) Ace View of F32A7.6
F32A7.6 Details Help
Description  an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles.
Homology Group (KOG)  Subtilisin-like proprotein convertase
GO Terms  defecation (GO:0030421) ; secretory pathway (GO:0045045) ; intracellular (GO:0005622) ; proprotein convertase activity (GO:0016808) ; subtilase activity (GO:0004289) ; proteolysis and peptidolysis (GO:0006508)
Location   I:14849654..14856174
RNAi Phenotypes
Larva Lva ; Gro ; Gro
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:174-f11
Adult Phenotypes  WT
RNAi Reagent Name & Type Cenix:174-f11 (PCR reagent)
Delivery Method  Injection
Remark  Wildtype results in all three tests.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F32A7.6
Embryonic Phenotypes  Emb Penetrance 10 %
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F32A7.6 (PCR reagent)
Laboratory  JA
Date  2000-11-16
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Simmer:F32A7.6:Screen_A
Larval Phenotypes  Gro
RNAi Reagent Name & Type sjj_F32A7.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Simmer:F32A7.6:Screen_B
Embryonic Phenotypes  Emb Penetrance 20 - 40 %
RNAi Reagent Name & Type sjj_F32A7.6 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
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