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Gene/ORF F33A8.5 Ace View of F33A8.5
F33A8.5 Details Help
Description  F33A8.5 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT D, INTEGRAL MEMBRANE PROTEIN (SDHD; OMIM:602690), which when mutated leads to disease.
Homology Group (KOG)  Succinate dehydrogenase membrane anchor subunit and related proteins
GO Terms  heme binding (GO:0020037) ; tricarboxylic acid cycle (GO:0006099) ; electron transport (GO:0006118) ; mitochondrial membrane (GO:0005740) ; integral to membrane (GO:0016021)
Location   II:11048622..11050230
RNAi Phenotypes
Postembryonic WT_postembryonic_morphology
Larva Lva ; Gro
Adult Clr
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Embryonic Phenotypes  Emb Penetrance 80 %
Larval Phenotypes  Gro
Adult Phenotypes  Clr
RNAi Reagent Name & Type sjj_F33A8.5 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Embryonic Phenotypes  Emb Penetrance 50 - 80 %
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_F33A8.5 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  WT_postembryonic_morphology
RNAi Reagent Name & Type Cenix:123-g4 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Clear cut.
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Gene Plot of F33A8.5 Browse using GBrowse
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