ORF Card Page


Gene/ORF F34D6.3 (sup-9)	Ace View of F34D6.3
F34D6.3 Details
Description	sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.
Homology Group (KOG)	Tandem pore domain K+ channel TASK3/THIK-1
GO Terms	potassium channel activity (GO:0005267) ; potassium ion transport (GO:0006813) ; membrane (GO:0016020)
Location	II:2684273..2687447
RNAi Phenotypes	No phenotypes observed.
External Links
Associated RNAi Experiments	View Details
Cenix:208-h11
Adult Phenotypes	WT
RNAi Reagent Name & Type	Cenix:208-h11 (PCR reagent)
Delivery Method	Injection
Remark	3/3 tests are wildtype
Laboratory	TH
Date	2005-3-24
Reference	Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F34D6.3
Adult Phenotypes	WT
RNAi Reagent Name & Type	sjj_F34D6.3 (PCR reagent)
Laboratory	JA
Date	2003-1-10
Reference	Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Gene Plot of F34D6.3	*Browse using GBrowse*