Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
Link to F35G12.8Link to F35G12.11.1Link to F35G12.11.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Gene/ORF F35G12.8 (smc-4) Ace View of F35G12.8
F35G12.8 Details Help
Description  The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation.
Homology Group (KOG)  Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C)
GO Terms  ATP binding (GO:0005524) ; ATPase activity (GO:0016887) ; chromosome organization and biogenesis (GO:0051276) ; chromosome (GO:0005694) ; protein binding (GO:0005515)
Location   III:4587071..4593474
RNAi Phenotypes
Early_embryo Pronuclei meet more centrally ; P2 and EMS divide synchronously ; Aberrant AB or P1 spindle orientation ; ABa, ABp and EMS divide synchronously ; Sister Chromatid Separation abnormal (Cross-eyed) ; Sister Chromatid Separation abnormal (Cross-eyed) ; Multiple cavities ; Multiple nuclei in 1, 2, or 4-cell embryos ; Division axis of ABa or ABp aberrant ; Delayed P0 spindle rotation ; Ectopic cleavage furrows ; Cytokinesis defect ; Nuclei reform next to cell division remnant
Postembryonic WT_postembryonic_morphology ; Larval Lethal-Early (L1/L2)
Larva Lva
Adult Pvl
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Details
Wild Type RNAi Experiments
Cenix:311-h1 WT
Experiments with Non-Wild Phenotypes
Cenix:310-g8 Emb ; WT_postembryonic_morphology
TH:340c12 Emb
TH:310G8 Emb
Cenix:340-c12 Emb ; Sister Chromatid Separation abnormal (Cross-eyed)
JA:F35G12.8 Emb ; Pvl
PF:GL1_4C11 ABa, ABp and EMS divide synchronously ; Aberrant AB or P1 spindle orientation ; Cytokinesis defect ; Delayed P0 spindle rotation ; Division axis of ABa or ABp aberrant ; Ectopic cleavage furrows ; Emb ; Lva ; Multiple cavities ; Multiple nuclei in 1, 2, or 4-cell embryos ; Nuclei reform next to cell division remnant ; P2 and EMS divide synchronously ; Pronuclei meet more centrally
Cenix:300-b1 Emb ; Sister Chromatid Separation abnormal (Cross-eyed)
TH:300b1 Emb
Cenix:329-g10 Larval Lethal-Early (L1/L2)
Simmer:F35G12.8 Emb
Gene Plot of F35G12.8 Browse using GBrowse
Gene Map