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Gene/ORF F37C12.11 (rps-21) Ace View of F37C12.11
F37C12.11 Details Help
Description  rps-21 encodes a small ribosomal subunit S21 protein; by homology, RPS-21 is predicted to function in protein biosynthesis; in C. elegans, RPS-21 activity is required for embryonic and germline development, as well as the overall health of the animal.
Homology Group (KOG)  40S ribosomal protein S21
GO Terms  structural constituent of ribosome (GO:0003735) ; protein biosynthesis (GO:0006412) ; intracellular (GO:0005622) ; ribosome (GO:0005840)
Location   III:7188663..7189962
RNAi Phenotypes
Early_embryo Severe Pleiotropic Defects
Larva Lva ; Lva
Adult Sck ; Ste ; Ste
External Links  wormbase.org NCBI.org NBrowse
Associated RNAi Experiments View Summary
Cenix:309-b4
Embryonic Phenotypes  Emb Penetrance None reported
Adult Phenotypes  Severe Pleiotropic Defects
RNAi Reagent Name & Type Cenix:309-b4 (PCR reagent)
Delivery Method  Injection
Remark  early embryonic: Severe Pleiotropic Defects
Laboratory  TH
Date  2005-3-24
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
JA:F37C12.11
Adult Phenotypes  Sck
Ste
RNAi Reagent Name & Type sjj_F37C12.11 (PCR reagent)
Laboratory  JA
Date  2003-1-10
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Simmer:F37C12.11
Larval Phenotypes  Lva
RNAi Reagent Name & Type sjj_F37C12.11 (PCR reagent)
Laboratory  NL
Date  2003-10-01
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
TH:309b4
Embryonic Phenotypes  Emb Penetrance None reported
RNAi Reagent Name & Type TH:309b4 (PCR reagent)
Remark  DIC phenotype -- Multiple female pronuclei; irregular cytoplasmic appearance; spindle unstable during anaphase; karyomeres in daughter blastomeres; nuclei in AB are off-center for a while, nuclei in P1 stay close to posterior cortex for a while. A bit slow overall.
Laboratory  TH
Date  2000-11-16
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Gene Plot of F37C12.11 Browse using GBrowse
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