Ace View of F37C12.11 | |||||||
F37C12.11 Details | |||||||
Description | rps-21 encodes a small ribosomal subunit S21 protein; by homology, RPS-21 is predicted to function in protein biosynthesis; in C. elegans, RPS-21 activity is required for embryonic and germline development, as well as the overall health of the animal. | ||||||
Homology Group (KOG) | 40S ribosomal protein S21 |
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GO Terms | structural constituent of ribosome (GO:0003735) ; protein biosynthesis (GO:0006412) ; intracellular (GO:0005622) ; ribosome (GO:0005840) | ||||||
Location | III:7188663..7189962 | ||||||
RNAi Phenotypes |
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External Links | |||||||
Associated RNAi Experiments | |||||||
Cenix:309-b4 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
Adult Phenotypes | Severe Pleiotropic Defects |
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RNAi Reagent Name & Type | Cenix:309-b4 (PCR reagent) | ||||||
Delivery Method | Injection | ||||||
Remark | early embryonic: Severe Pleiotropic Defects | ||||||
Laboratory | TH | ||||||
Date | 2005-3-24 | ||||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||
JA:F37C12.11 | |||||||
Adult Phenotypes | Sck Ste |
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RNAi Reagent Name & Type | sjj_F37C12.11 (PCR reagent) | ||||||
Laboratory | JA | ||||||
Date | 2003-1-10 | ||||||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||||||
Simmer:F37C12.11 | |||||||
Larval Phenotypes | Lva |
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RNAi Reagent Name & Type | sjj_F37C12.11 (PCR reagent) | ||||||
Laboratory | NL | ||||||
Date | 2003-10-01 | ||||||
Strain | NL4256 rrf-3(pk1426) | ||||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||
TH:309b4 | |||||||
Embryonic Phenotypes | Emb Penetrance None reported | ||||||
RNAi Reagent Name & Type | TH:309b4 (PCR reagent) | ||||||
Remark | DIC phenotype -- Multiple female pronuclei; irregular cytoplasmic appearance; spindle unstable during anaphase; karyomeres in daughter blastomeres; nuclei in AB are off-center for a while, nuclei in P1 stay close to posterior cortex for a while. A bit slow overall. | ||||||
Laboratory | TH | ||||||
Date | 2000-11-16 | ||||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||
Gene Plot of F37C12.11 | |||||||